Rapid Migration of Inositol Phospholipids with Axonally Transported Substances in the Rabbit Optic Pathway

Abstract
Following an intraocular injection of myo-[2-3H]inositol, the axonal transport of labeled water-soluble substances and inositol phospholipids was investigated. Evidence was obtained for a rapid axonal transport of a relatively small amount of labeled inositol phospholipids. In contrast to other axonally transported phospholipids, there was no significant accumulation of labeled, rapidly transported inositol phospholipids in the nerve terminal region at later time intervals following isotope administration.

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