Reactive intermediates in laser photolysis of guanosine
- 1 September 1991
- journal article
- Published by Springer Nature in Research on Chemical Intermediates
- Vol. 15 (3) , 293-301
- https://doi.org/10.1163/156856791x00390
Abstract
The photochemical reactions of aqueous solution guanosine with acetone as photosensitizer have been investigated by laser flash photolysis. From detailed kinetic analysis, the reaction mechanism has been derived: dehydrogenated guanosine radical G(-H)* and triplet guanosine 3G* were produced via electron transfer and triplet-triplet energy transfer respectively. The half-life time of 3G* has been determined to be 7.4 μs, and the quenching rate constant of Mn2+ on it was obtained to be 1.9 × 108 M-1 s-1. Based on pH titration, the pKa value of 3G* was also obtained to be 8.7.Keywords
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