VIP modulation of cultured glial cells of the rat retina
- 1 January 1989
- journal article
- research article
- Published by Taylor & Francis in Current Eye Research
- Vol. 8 (11) , 1207-1210
- https://doi.org/10.3109/02713688909000045
Abstract
Cultured retinal glial cells from the rat are responsive to modulation by vasoactive intestinal peptide (VIP). VIP (IX 10−6M) elevated the intracellular cyclic AMP concentration from the basal level of (4.4–11.1) p mole/mg protein to (354–440) p mole/mg protein in threi minutes at 25oC. The half-maximal concentration is 4.8X10−8M, which is similar to that observed in the cultured retinal glial cells from the chick embryo.Keywords
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