Natriuretic and diuretic effects of salmon calcitonin in rats
- 1 December 1970
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 48 (12) , 838-841
- https://doi.org/10.1139/y70-122
Abstract
Injection of salmon calcitonin into rats caused a significant increase in the excretion of sodium and water in a dose as small as 4 × 10−9 g. There appeared to be a linear relationship between sodium excretion and the log dose of calcitonin. Potassium excretion and free-water clearance were not significantly affected. Thyroparathyroidectomized rats showed no impairment in their ability to excrete sodium either before or after saline loading.Keywords
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