Abstract
At least two generations of grandmothers are responsible for the hysteria that usually surrounds a case of fulminant meningitis. Epidemics of "cerebrospinal, spotted fevers" in the United States in the 1880's, 1917–1918 and 1942–1943 gave rise to an almost instinctive fear of meningitis. Each case of the dreaded disease (meningococcal sepsis or meningitis) brought concern that it might be the harbinger of a new epidemic. Grandmother was correct about the contagiousness of meningococcal disease; the secondary attack rate exceeds the primary rate in the general population by 700-fold1 — a risk that prompts prophylactic intervention.On the other hand, an . . .