THE MECHANISM OF PAIN IN GASTRIC AND DUODENAL ULCERS
- 1 November 1926
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 38 (5) , 603-611
- https://doi.org/10.1001/archinte.1926.00120290052006
Abstract
INTRODUCTION The genesis of pain arising from the stomach and intestine as the result of both functional and organic disorders has attracted much attention in recent years. Inflammation, muscle tension, acid irritation, edema, peritoneal irritation and perineural infiltration have all been ascribed their various rôles. The present work was undertaken with the hope that some aid might be obtained from a clearer understanding of the mechanism of pain in gastric and duodenal ulcers. It has naturally led into other fields at times, but attention has been focused chiefly on the benign peptic ulcer. One of the first problems encountered was that of the occurrence of ulcer and ulcer pain with achlorhydria. LITERATURE In the literature many allusions are found to ulcers with achlorhydria, but few of them are definite. For instance, in 1911, Gibson1stated that the free acidity in his ulcer cases varied from 0 to 0.18 per cent.This publication has 0 references indexed in Scilit: