Abstract
A series of tests relative to the egg stage of S. mansoni have been investigated at various intervals after infection of white mice, in an attempt to study the chronology of host-parasite interaction. These comprise: egg counts in faeces, weight of liver and spleen, histological reaction in liver and terminal ileum to different stages of the egg, and the serological reactions leading to miracidial immobilization, circumoval precipitates, and inhibition of the proteolytic enzyme secreted by the egg.

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