Antinuclear Antibody Factors and Nuclear Staining in Mothers of Children Affected with Down's Syndrome
- 1 April 1970
- journal article
- research article
- Published by Cambridge University Press (CUP) in Acta geneticae medicae et gemellologiae
- Vol. 19 (4) , 529-533
- https://doi.org/10.1017/s1120962300014566
Abstract
Summary: Sera from 50 mothers of G1-trisomy affected children and from 50 age-matched mothers, whose offspring included no chromosomal-aneuploidy affected children, were tested for presence of antinuclear antibody factors and nuclear staining with human squamous epithelium and with mouse liver. Consistently, more of the mothers of G1-trisomy affected children included positive findings in both tests, compared to the age-matched mothers.Keywords
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