Cross-reaction between Streptococcus pneumoniae and group C streptococcal latex reagent

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Abstract
The extent of cross-reactivity between Streptococcus pneumoniae and two commercial streptoccocal latex grouping reagents was examined. Cross-reactivity with the group C latex reagent was demonstrated in 91% (20 of 22) of blood cultures tested directly and in 97% (73 of 75) of clinical isolates of various serotypes tested after enzymatic extraction. This is the important in the clinical laboratory because it may lead to erroneous identification of organiams present in blood cultures.