Structural and functional analysis of the rat malic enzyme gene promoter.
Open Access
- 1 August 1988
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 8 (8) , 3542-3545
- https://doi.org/10.1128/mcb.8.8.3542
Abstract
We have characterized sequences of genomic DNA 5' to the coding region of the rat malic enzyme gene. This sequence possesses neither TATA nor CCAAT sequences in their usual positions but is rich in GC residues. Sequences similar to those found in the regulatory regions of other genes are discussed. Deletion analyses have revealed that sequences +1 to -41 are sufficient to initiate expression, although inclusion of information up to -177 is necessary for maximal promoter activity.This publication has 33 references indexed in Scilit:
- Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk geneCell, 1986
- Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expressionCell, 1986
- Expression of the mouse HPRT gene: Deletional analysis of the promoter region of an X-Chromosome linked housekeeping geneCell, 1985
- Promoter Region of the Human Harvey ras Proto-Oncogene: Similarity to the EGF Receptor Proto-Oncogene PromoterScience, 1985
- Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinaseGene, 1984
- HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regionsCell, 1984
- Functional analysis of the nucleotide sequence surrounding the cap site for adenovirus type 5 region E1A messenger RNAsJournal of Molecular Biology, 1983
- Transcriptional Control Signals of a Eukaryotic Protein-Coding GeneScience, 1982
- Organization and Expression of Eucaryotic Split Genes Coding for ProteinsAnnual Review of Biochemistry, 1981
- Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseBiochemistry, 1979