Potentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of extracellular signal-regulated kinase1/2 (ERK1/2) in conjunction with p38 kinase or c-jun N-terminal kinase (JNK): Complete inhibition of the potentiated toxicity by U0126 an ERK1/2 and p38 kinase inhibitor
- 15 December 2001
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 62 (10) , 1379-1390
- https://doi.org/10.1016/s0006-2952(01)00780-8
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Changes in hepatic glutathione concentration modify cadmium-induced hepatotoxicityPublished by Elsevier ,2004
- Prevention of c-Jun/activator protein-1 activation and microsomal epoxide hydrolase induction in the rat liver by cysteine during protein–calorie malnutritionBiochemical Pharmacology, 2000
- The Essential Role of Phosphatidylinositol 3-Kinase and of p38 Mitogen-Activated Protein Kinase Activation in the Antioxidant Response Element-Mediated rGSTA2 Induction by Decreased Glutathione in H4IIE Hepatoma CellsMolecular Pharmacology, 2000
- The effect of cysteine on the altered expression of class α and μ glutathione S-transferase genes in the rat liver during protein–calorie malnutritionBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2000
- Cadmium-Induced Apoptosis in Mouse LiverToxicology and Applied Pharmacology, 1998
- Induction of metallothionein as an adaptive mechanism affecting the magnitude and progression of toxicological injury.Environmental Health Perspectives, 1998
- Role of Metallothionein in Cadmium-Induced Hepatotoxicity and NephrotoxicityDrug Metabolism Reviews, 1997
- Cellular defenses against damage from reactive oxygen speciesPhysiological Reviews, 1994
- [3] Toxicological significance of metallothioneinPublished by Elsevier ,1991
- Glutathione, a first line of defense against cadmium toxicityThe FASEB Journal, 1987