Different Predictors of Neurological Worsening in Different Causes of Stroke
Open Access
- 1 April 1998
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 55 (4) , 481-486
- https://doi.org/10.1001/archneur.55.4.481
Abstract
WORSENING of neurological symptoms after acute cerebrovascular disease has always interested clinicians and was formally reported by Millikan and Siekert1,2 more than 40 years ago. Although various terms, such as progressive stroke, stroke-in-progression, or stroke-in-evolution, as well as various concepts about temporal profile have been proposed since then, there has not been any generally accepted term or definition for this clinical setting.3 This might be related in part to the lack of an effective specific treatment. Indeed, although the use of heparin is commonly recommended in patients with neurological worsening associated with acute ischemic stroke, its effectiveness remains controversial.4-7Keywords
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