Toxic Thromboplastic Extracts of Skin

Publisher Website
Google Scholar
Abstract
IN 1962 IN THE US, 1.8 million patients were hospitalized with extensive burns and there were 11,500 deaths.1Despite advances in knowledge of the pathology of thermal burns, mortality remains high with many deaths occurring after the initial shock. These "late deaths" are frequently ascribed to pulmonary involvement or infection. The initial treatment for shock is primarily replacement of body fluids accomplished by administration of large volumes of fluids, including solutions of sodium salts, colloidal solutions such as plasma, albumin, or dextran, and whole blood. It is noteworthy that in various hospitals in the US and in burn centers in Europe, widely differing combinations of these fluids are utilized.2In seeking improvements in therapy it is essential to reevaluate the experimental work to ascertain both the therapeutic potential and the limitations of fluid replacement.1Recently, S. M. Rosenthal compared the overall effect of fluid therapy in burn shock and

This publication has 0 references indexed in Scilit: