A Molecular Marker for Chloroquine-Resistant Falciparum Malaria

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Abstract
Malaria caused by Plasmodium falciparum, a protozoan parasite of the blood, is responsible for up to 2.7 million deaths yearly, mainly in children in sub-Saharan Africa. Worldwide there are over 300 million new cases of malaria per year. Given the lack of a suitable vaccine, the main ways to reduce morbidity and mortality are the use of insecticide-impregnated netting around the bed and chemoprophylaxis for specific groups at increased risk, such as nonimmune travelers to an area where malaria is endemic, pregnant women,1 and children with sickle cell anemia. However, in many areas the effectiveness of treatment and of efforts . . .