Mechanism of Cholesterol Transfer from the Niemann-Pick Type C2 Protein to Model Membranes Supports a Role in Lysosomal Cholesterol Transport
- 10 April 2006
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 281 (42) , 31594-31604
- https://doi.org/10.1074/jbc.m602765200
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transportProceedings of the National Academy of Sciences, 2004
- The integrity of a cholesterol-binding pocket in Niemann–Pick C2 protein is necessary to control lysosome cholesterol levelsProceedings of the National Academy of Sciences, 2003
- Identification of HE1 as the Second Gene of Niemann-Pick C DiseaseScience, 2000
- Role of Niemann-Pick Type C1 Protein in Intracellular Trafficking of Low Density Lipoprotein-derived CholesterolJournal of Biological Chemistry, 2000
- A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterolBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1999
- Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol HomeostasisScience, 1997
- Complementation studies in Niemann-Pick disease type C indicate the existence of a second group.Journal of Medical Genetics, 1994
- The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterolBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
- Type C Niemann-Pick disease: spectrum of phenotypic variation in disruption of intracellular LDL-derived cholesterol processingBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1991
- The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts.The Journal of cell biology, 1989