Top-down identification and characterization of biomolecules by mass spectrometry
- 1 August 2008
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Society for Mass Spectrometry
- Vol. 19 (8) , 1045-1053
- https://doi.org/10.1016/j.jasms.2008.05.013
Abstract
The most widely used modern mass spectrometers face severe performance limitations with molecules larger than a few kDa. For far larger biomolecules, a common practice has been to break these up ch...Keywords
This publication has 92 references indexed in Scilit:
- Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cellsProceedings of the National Academy of Sciences, 2008
- Decoding protein modifications using top-down mass spectrometryNature Methods, 2007
- ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometryNucleic Acids Research, 2007
- Implementation of Electron-Transfer Dissociation on a Hybrid Linear Ion Trap−Orbitrap Mass SpectrometerAnalytical Chemistry, 2007
- Mass spectrometry-based detection of transfer RNAs by their signature endonuclease digestion productsRNA, 2006
- Mass spectrometry of RNA: linking the genome to the proteomeBriefings in Functional Genomics and Proteomics, 2006
- Mass spectrometry-based proteomicsNature, 2003
- Peer Reviewed: Scaling MS Plateaus with High-Resolution FT-ICRMSAnalytical Chemistry, 2002
- Fourier transform ion cyclotron resonance mass spectrometry: A primerMass Spectrometry Reviews, 1998
- Determination of amino acid sequences in peptide mixtures by mass spectrometryBiochemical and Biophysical Research Communications, 1970