EVIDENCE FOR A MECHANISM OF SODIUM-INDUCED CALCIUM RELEASE IN FROG AURICULAR TRABECLES
- 1 January 1980
- journal article
- research article
- Vol. 291 (6) , 557-560
Abstract
In a Ca-free, Mg-free medium containing EGTA [ethyleneglycol bis[.beta.-aminoethyl ether] N,N''-tetraacetic acid] (10-3 M) auricular trabecles develop a slow inward current which is a pure Na current. After 12 min in this medium, it is still possible to obtain a phasic mechanical activity which shows a perfect correlation with the current. A mechanism of Na-induced Ca release apparently is present at the level of some internal sites.This publication has 2 references indexed in Scilit:
- Sodium-induced calcium release from mitochondria in brown adipose tissue.Proceedings of the National Academy of Sciences, 1979
- A study of the ion selectivity and the kinetic properties of the calcium dependent slow inward current in mammalian cardiac muscle.The Journal of Physiology, 1977