Determination of 4-Hydroxy-3-Methoxymandelic Acid in Urine using HPLC with Electrochemical Detection
- 1 March 1987
- journal article
- research article
- Published by SAGE Publications in Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
- Vol. 24 (2) , 172-176
- https://doi.org/10.1177/000456328702400208
Abstract
A method is described for the assay of 4-hydroxy-3-mcthoxymandelic acid (HMMA) in urine using IIPLC coupled with electrochemical detection. In this method acidified urine is extracted with ethyl acetate which is then washed with the chromatography solvent to back extract HMMA. The solvent is a pH 50 citrate buffer. At this pH, HMMA separates clearly from all other electroactive compounds present in urine.This publication has 7 references indexed in Scilit:
- Urinary 4-hydroxy-3-methoxymandelic (vanillylmandelic) acid, 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid, and 5-hydroxy-3-indoleacetic acid determined by liquid chromatography with electrochemical detection.Clinical Chemistry, 1983
- Determination of urinary vanillylmandelic acid by liquid chromatography with electrochemical detection.Clinical Chemistry, 1983
- Simultaneous liquid-chromatographic analysis for 4-hydroxy-3-methoxymandelic acid and 4-hydroxy-3-methoxyphenylacetic acid in urine.Clinical Chemistry, 1980
- SIMULTANEOUS LIQUID-CHROMATOGRAPHIC ANALYSIS FOR 4-HYDROXY-3-METHOXYMANDELIC ACID AND 4-HYDROXY-3-METHOXYPHENYLACETIC ACID IN URINE1980
- Assay of urinary 4-hdyroxy-3-methoxymandelic (vanillylmandelic) acid by liquid chromatography with electrochemical detection.Clinical Chemistry, 1979
- Determination of 3-methoxy-4-hydroxymandelic acid in urineClinica Chimica Acta; International Journal of Clinical Chemistry, 1962
- A simple analysis for normetanephrine and metanephrine in urineClinica Chimica Acta; International Journal of Clinical Chemistry, 1960