AGENESIS OF THE CORPUS CALLOSUM WITH POSSIBLE PORENCEPHALY

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Abstract
The accumulation of reported data from twenty-five years of pneumoencephalographic studies has directed the interest of neurosurgeons to certain rare anomalous conditions of the brain which may be demonstrated in the encephalogram. These include agenesis of the corpus callosum, porencephalic cysts and cysts of the cavum septi pellucidi and the cavum Vergae. Interesting as these lesions are from a morphologic and a diagnostic standpoint, their study may be especially important because of the possibility that some abnormalities of mental and physical development, hitherto attributed to birth injury, may originate in embryonic or developmental defects of the brain. In this paper are reviewed all the reported cases in the English literature in which an antemortem diagnosis of agenesis of the corpus callosum was made. An additional case associated with a suspected porencephalic cyst is reported. Cysts of the cavum septi pellucidi and the cavum Vergae are discussed under "Differential Diagnosis." HISTORICAL