CYTOCHALASIN-B STABILIZES SUB-CORTICAL ACTIN BUNDLES OF CHARA AGAINST A SOLUTION OF LOW IONIC-STRENGTH

  • 1 January 1978
    • journal article
    • research article
    • Vol. 18  (1) , 107-113
Abstract
The properties of the sub-cortical actin bundles in the perfused Chara [C. corallina] cell model are altered by concentrations of cytochalasin B (CB) which inhibit streaming. The bundles were treated with intracellularly introduced CB after 1st using STP to strip away their associated motile organelles. Such CB-treated bundles are resistant to a solution of low ionic strength which, as judged by light and EM, extracts untreated bundles. A site of action for CB lies within the actin bundles. While the alteration detected may not itself be of direct physiological significance, it may nonetheless indicate the site at which CB inhibits streaming in both the cell model and the intact cell.