Enantioselective Palladium Catalyzed Allylic Amination Using New Chiral Pyridine-Phosphine Ligands

Abstract
Asymmetric palladium catalyzed allylic amination of 5 with various amines has been studied using a new class of chiral pyridine-phosphine ligands. High enantioselectivities of up to 94% ee have been observed using benzylamine, veratrylamine or morpholine as nucleophiles.

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