Effects of Blood Pressure Level on Progression of Diabetic NephropathyResults From the RENAAL Study
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Open Access
- 14 July 2003
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 163 (13) , 1555-1565
- https://doi.org/10.1001/archinte.163.13.1555
Abstract
POST HOC ANALYSES of clinical trials that involve participants with type 2 diabetes mellitus as well as longitudinal follow-up studies of people with hypertension without diabetes demonstrate a clear association between the degree of systolic blood pressure (SBP) elevation and cardiovascular risk.1-3 Additionally, long-term follow-up data involving more than 10 000 men from a Veterans Administration study showed that SBP was an independent risk factor for renal disease progression.4 Until recently, no clinical trial has recruited participants with predominately systolic hypertension to evaluate the impact of SBP on renal outcomes.Keywords
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