HER-2/neu and p53 Expression Versus Tamoxifen Resistance in Estrogen Receptor–Positive, Node-Positive Breast Cancer
- 20 October 2000
- journal article
- research article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 18 (20) , 3471-3479
- https://doi.org/10.1200/jco.2000.18.20.3471
Abstract
PURPOSE: An association between the overexpression of proto-oncogene HER-2/neu and resistance to tamoxifen in estrogen receptor (ER)–positive primary and metastatic breast cancer has been suggested...Keywords
This publication has 18 references indexed in Scilit:
- Overexpression of c-erbB2 is an independent marker of resistance to endocrine therapy in advanced breast cancerBritish Journal of Cancer, 1999
- Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein.Journal of Clinical Oncology, 1997
- Variation of hormonal receptor, pS2, c-erbB-2 and GSTπ contents in breast carcinomas under tamoxifen: a study of 74 casesBritish Journal of Cancer, 1996
- Relation of oestradiol-mediated growth stimulation with the expression of c-erbB-2 protein in xenotransplanted oestradiol-receptor-positive and -negative breast carcinomasZeitschrift für Krebsforschung und Klinische Onkologie, 1996
- Oncogene amplification and prognosis in breast cancer: Relationship with systemic treatmentGene, 1995
- Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer.Journal of Clinical Oncology, 1995
- ERBB2 amplification is associated with tamoxifen resistance in steroid-receptor positive breast cancerCancer Letters, 1994
- Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neuBreast Cancer Research and Treatment, 1992
- Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancerBritish Journal of Cancer, 1992
- Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu OncogeneScience, 1985