Distribution of the modified nucleoside Q and its derivatives in animal and plant transfer RNA's
- 1 January 1975
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 2 (10) , 1931-1940
- https://doi.org/10.1093/nar/2.10.1931
Abstract
The modified nucleoside, 7-(4,5-cis-dihydroxy-1-cyclopenten-3-yl-aminomethyl)-7-deazaguanosine, designated as Q, and its derivative, Q*, were found in tRNA's from various organisms, including several mammalian tissues, other animals such as starfish, lingula and hagfish, and wheat germ. Q isolated from rat liver tRNA was found to be identical with E. coli Q by mass spectrometry and thin-layer chromatography. Thus the rare modified nucleoside Q originally isolated from E. coli tRNA, is widely distributed in various organisms. Analysis of the mass spectrum of Q* suggested that it has a different side chain from Q.Keywords
This publication has 9 references indexed in Scilit:
- Alterations in SVT2 cell transfer RNAs in response to cell density and serum typeBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975
- Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locusJournal of Molecular Biology, 1973
- Possible anticodon sequences of tRNAHis, tRNAAsn, and tRNAAsp from Escherichia coli. Universal presence of nucleoside O in the first position of the anticodons of these transfer ribonucleic acidBiochemistry, 1972
- The altered patterns of transfer RNA in SV40-infected and transformed cellsVirology, 1972
- Minor dinucleotides of rat-liver transfer RNABiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969
- DIFFERENCES IN THE TRANSFER RNA'S OF NORMAL LIVER AND NOVIKOFF HEPATOMAProceedings of the National Academy of Sciences, 1969
- Purification of histidine-specific transfer RNA from yeastBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1967
- Resolution of Multiple Ribonucleic Acid Species by Polyacrylamide Gel Electrophoresis*Biochemistry, 1967
- A simplified procedure for the preparation of “soluble” RNA from rat liverBiochemical and Biophysical Research Communications, 1962