Osteogenesis Imperfecta

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Abstract
Twelve families with 29 patients showing various patterns of osteogenesis imperfecta are described, along with the genetic, pathological, and clinical features. No abnormal biochemical features were found. It has been shown that the best treatment is prophylactic (such as intramedullary nailing) or supportive. There was no remarkable improvement from any form of medical treatment. These data are compared to those of other authors.

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