In Vitro Activities of the Newer Quinolones Garenoxacin, Gatifloxacin, and Gemifloxacin against Human Mycoplasmas
Open Access
- 1 August 2004
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (8) , 3165-3168
- https://doi.org/10.1128/aac.48.8.3165-3168.2004
Abstract
The activities of garenoxacin, gatifloxacin, and gemifloxacin were compared with those of four fluoroquinolones against human mycoplasmas and ureaplasmas, including fluoroquinolone-resistant genetically characterized strains. Garenoxacin exhibited the highest activity, followed by gemifloxacin, moxifloxacin, and gatifloxacin. The minimal bactericidal activities of these three compounds were lower than those of the four fluoroquinolones.Keywords
This publication has 15 references indexed in Scilit:
- Inhibitory and bactericidal activities of gemifloxacin and other antimicrobials against Mycoplasma pneumoniaeInternational Journal of Antimicrobial Agents, 2003
- In Vitro Susceptibilities to and Bactericidal Activities of Garenoxacin (BMS-284756) and Other Antimicrobial Agents against Human Mycoplasmas and UreaplasmasAntimicrobial Agents and Chemotherapy, 2003
- Susceptibilities of Mycoplasma hominis, M. pneumoniae , and Ureaplasma urealyticum to GAR-936, Dalfopristin, Dirithromycin, Evernimicin, Gatifloxacin, Linezolid, Moxifloxacin, Quinupristin-Dalfopristin, and Telithromycin Compared to Their Susceptibilities to Reference Macrolides, Tetracyclines, and QuinolonesAntimicrobial Agents and Chemotherapy, 2001
- Antibacterial Spectrum of a Novel Des-Fluoro(6) Quinolone, BMS-284756Antimicrobial Agents and Chemotherapy, 2000
- In vitro antibacterial spectrum of a new broad-spectrum 8-methoxy fluoroquinolone, gatifloxacinJournal of Antimicrobial Chemotherapy, 2000
- Comparative in vitro activity of gemifloxacinJournal of Antimicrobial Chemotherapy, 2000
- Review of the in vitro activity of gemifloxacin against Gram-positive and Gram-negative anaerobic pathogensJournal of Antimicrobial Chemotherapy, 2000
- Comparative potency of gemifloxacin, new quinolones, macrolides, tetracycline and clindamycin against Mycoplasma spp.Journal of Antimicrobial Chemotherapy, 2000
- The in-vitro activity and tentative breakpoint of gemifloxacin, a new fluoroquinoloneJournal of Antimicrobial Chemotherapy, 1999
- Mutations in the gyrA , parC , and parE Genes Associated with Fluoroquinolone Resistance in Clinical Isolates of Mycoplasma hominisAntimicrobial Agents and Chemotherapy, 1999