Abstract
The author gives a description of recent work bearing on the diversity of effects obtained in the motor neurone by reflex stimulation. Afferent stimuli produce states of excitement or of inhibition in the central nervous tissue, the effects of which on the motor neurone may be summation of excitement, summation of inhibition or the algebraic summation of the two. The central reactions are of longer duration than the nerve impulse of nerve trunks. Also these central processes are relatively sensitive to fatigue, variations in bloodsupply, drugs, etc. The central neurones modify the impulses which they transmit and can develop a rhythm of their own, so that the rate of their discharge can rise and fall with the intensity of central excitation and inhibition respectively.

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