Effect of Nicotinic Acid on Serum Triglyceride, Cholesterol and Chylomicrons in Rats

Abstract
Summary The effects of nicotinic acid on serum lipids have been studied in rats. Significant decreases in serum triglyceride and cholesterol were observed in fasted rats 4 hours after oral administration of nicotinic acid. Greater reductions in triglyceride occurred than in cholesterol. In addition, in another study, oral or parenteral administration of nicotinic acid significantly inhibited fat-induced chylomicronemia.

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