GROWTH HORMONE CELL ANTIBODIES AND PARTIAL GROWTH HORMONE DEFICIENCY IN A GIRL WITH TURNER'S SYNDROME

Abstract
Growth hormone (GH) cell auto-antibodies were demonstrated in the serum of a girl with an isochromosome variant of Turner''s syndrome. On 2 occasions she showed an abnormal response of GH release during insulin-induced hypoglycemia. Her response to GH treatment was poor, but this began at a very late bone-age. It is possible that autoimmunity is a new etiological factor for GH deficiency in some cases.

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