Circulating Osteoblast-Lineage Cells in Humans
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Open Access
- 12 May 2005
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 352 (19) , 1959-1966
- https://doi.org/10.1056/nejmoa044264
Abstract
Although current evidence suggests that only a minuscule number of osteoblast-lineage cells are present in peripheral blood, we hypothesized that such cells circulate but that their concentration has been vastly underestimated owing to the use of assays that required adherence to plastic. We further reasoned that the concentration of these cells is elevated during times of increased bone formation, such as during pubertal growth.Keywords
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