Liver tumours after single dose dimethylnitrosamine, low and high protein diet, and phenobarbitone
- 1 January 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 3 (6) , 707-709
- https://doi.org/10.1093/carcin/3.6.707
Abstract
A single dose of 15 mg/kg dimethylnitrosamine given to rats at the time of switch from low to high protein diet is an effective initiator of hepatic tumour formation. With phenobarbitone as promoter, a high yield of liver tumours is produced. The switch from low to high protein diet may be a way of enhancing tumour initiation hi many tissues.This publication has 6 references indexed in Scilit:
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