Effects of in vivo Hyperoxia on Erythrocytes 1. Hemolysis in Mice Exposed to Hyperbaric Oxygenation.
- 1 June 1964
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 116 (2) , 259-261
- https://doi.org/10.3181/00379727-116-29218
Abstract
Summary In vivo lytic sensitivity of mouse erythrocytes to hyperbaric oxygenation paralleled their in vitro sensitivity to H2O2. In vitro lysis was associated with lipid peroxide formation. The in vivo and in vitro lysis and in vitro lipid peroxide formation were enhanced by vit. E deficiency and reduced by treatment of animals with a tocopherol acetate. It was suggested that hyperoxic hemolysis in vivo was a direct or indirect result of abnormal lipid peroxidation.Keywords
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