Primary central nervous system lymphoma related to Epstein‐Barr virus in a patient with acquired immune deficiency syndrome

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Abstract
The study of a patient suggested a relationship between Epstein‐Barr virus infection and primary lymphoma of the central nervous system in the acquired immune deficiency syndrome. Deoxyribonucleic acid preparations from tumor tissue contained 30 to 100 copies of Epstein‐Barr virus genome per cell when hybridized with a probe consisting of the Bam‐HI K fragment of Epstein‐Barr virus strain FF41. This hybridization study suggests that induction of this patient's central nervous system lymphoma was related to Epstein‐Barr virus infection.