De novo 3q/7q translocation and associated interstitial 7q35 deletion
- 1 January 1988
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 33 (1) , 60-62
- https://doi.org/10.1111/j.1399-0004.1988.tb04267.x
Abstract
In the present report we describe a severely mentally retarded and dysmorphic female child with a de novo 3q/7q reciprocal translocation and loss of band 7q35. This finding supports the hyothesis that the occurrence of mental retardation and/or congenital malformations in de novo autosomal reciprocal translocation may be due to the loss of a small amount of chromatin material during this chromosomal rearrangement.Keywords
This publication has 3 references indexed in Scilit:
- Excess of mental retardation and/or congenital malformation in reciprocal translocations in manHuman Genetics, 1986
- Clinical, chromosomal and enzymatic studies in four cases of rearrangements of chromosome 7*Clinical Genetics, 1985
- Terminal and interstitial deletions of the long arm of chromosome 7: A review with five new casesAmerican Journal of Medical Genetics, 1984