Colonic Anastomosis Healing

Abstract
The effect of povidone-iodine (0.1% available I) irrigation on colonic anastomosis healing was investigated in 196 Sprague-Dawley rats. Each end of the divided colon was irrigated with 5 ml of povidone-iodine solution or with an equal volume of normal saline before anastomosis and again after the anastomosis was completed. Healing was assessed at 2, 4, 6, 8, 10 and 14 days after operation: macroscopically, mechanically, histologically and angiographically. Povidone-iodine irrigation did not impair healing in any way.

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