Identification and localization of Giα3 in the clonal adipocyte cell lines HGFu and Obl7
- 1 December 1993
- journal article
- research article
- Published by Canadian Science Publishing in Biochemistry and Cell Biology
- Vol. 71 (11-12) , 518-521
- https://doi.org/10.1139/o93-074
Abstract
The HGFu and Ob17 cell lines, derived from adipose tissue of lean (+/?) and ob/ob mice, respectively, express several G-protein peptides. Investigation of the expression and subcellular localization of the Giα3 subunit showed that this peptide is associated with the Golgi apparatus. These findings indicate a role for this subunit in vesicular traffic and are in agreement with the view of the adipocyte as a secretory cell.Key words: preadipocytes, differentiation, immunofluorescence, confocal microscopy, obesity, Golgi system.Keywords
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