Cholera
- 1 January 1973
- journal article
- research article
- Published by Taylor & Francis in CRC Critical Reviews in Microbiology
- Vol. 2 (4) , 553-623
- https://doi.org/10.3109/10408417309108394
Abstract
“It is an erroneous impression, fostered by sensational popular biography, that scientific discovery is often made by inspiration - a sort of coup defoudre - from on high. This is rarely the case. Even Archimedes' sudden inspiration in the bathtub; Newton's experience in the apple orchard; Descartes's geometrical discoveries in his bed; Darwin's flash of lucidity on reading a passage in Malthus; Kekulé's vision of the closed carbon ring which came to him on top of a London bus; and Einstein's brilliant solution of the Michelson puzzle in the patent office in Beme, were not messages out of the blue. They were the final coordinations, by minds of genius, of innumerable accumulated facts and impressions which lesser men could grasp only in their uncorrelated isolation, but which—by them - were seen in entirety and integrated into general principles. The scientist takes off from the manifold observations of predecessors, and shows his intelligence, if any, by his ability to discriminate between the important and the negligible, by selecting here and there the significant stepp ings tones that will lead across the difficulties to new understanding. The one who places the last stone and steps across to the terra finna of accomplished discovery gets all the credit. Only the initiated know and honor those whose patient integrity and devotion to exact observation have made the last step possible.”Keywords
This publication has 98 references indexed in Scilit:
- The effect of cholera toxin on the phosphorylation of protein in epithelial cells and their brush bordersBiochemical and Biophysical Research Communications, 1972
- Orale Immunisierung mit abgetöteten BakterienInternational Journal of Public Health, 1972
- Purification of neuraminidases from Vibrio cholerae, Clostridium perfringens and influenza virus by affinity chromatographyBiochemical and Biophysical Research Communications, 1971
- Immunochemical studies of the O‐antigens of Vibrio cholerae. The constitution of a lipopolysaccharide from V. cholerae 569B (Inaba)FEBS Letters, 1971
- Bioassay of Endotoxin: Correlation Between Pyrogenicity for Rabbits and Lethality for Chick EmbryosThe Journal of Infectious Diseases, 1966
- EXPERIMENTAL CHOLERA A CANINE MODELThe Lancet, 1966
- Virulence of El Tor Vibrios for Chick EmbryosNature, 1964
- Genetic Recombination in Vibrio choleraeNature, 1961
- NON-SPECIFIC RESISTANCE TO EXPERIMENTAL CHOLERA IN EMBRYONATED EGGSThe Journal of Experimental Medicine, 1960
- COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERAThe Journal of Experimental Medicine, 1956