Studies on Chemical Carcinogens. I. Reduction of 4-Substituted Quinoline N-Oxide with Sodium Borohydride

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Abstract
4-Substituted quinoline N-oxides were reduced by sodium borohydride and the reaction mechanism was discussed. It was revealed, for example, that 4-nitroquinoline N-oxide underwent competitive nu-cleophilic reactions to produced denitrated quinoline N-oxide, deoxy-genated 4-nitroquinoline and 4-hydroxylaminoquinoline N-oxide which is a reduction product of nitro group, respectively.