SEROLOGICAL EVIDENCE OF THE ANTIGENICITY OF OX ANTERIOR PITUITARY GROWTH HORMONE IN SHEEP

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Abstract
Using the tannic acid haemagglutination test, antibodies reacting with a purified preparation of ox growth hormone were detected in the sera of sheep following injection with crude anterior pituitary extract or with purified ox growth hormone. Prior absorption of the sera with various anterior pituitary preparations rich in ox growth hormone inhibited haemagglutination. Absorption of the sera with anterior pituitary preparations containing negligible amounts of growth hormone or with ox serum did not inhibit haemagglutination. It is concluded that ox growth hormone is antigenic in the sheep.

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