Production of 3-Methyl-6-Methoxy-8-Hydroxy-3,4-Dihydroisocoumarin by Aspergillus caespitosus
- 1 January 1975
- journal article
- research article
- Published by American Society for Microbiology in Applied Microbiology
- Vol. 29 (5) , 706-707
- https://doi.org/10.1128/aem.29.5.706-707.1975
Abstract
Aspergillus caespitosus Raper and Thom cultured on autoclaved cracked, yellow field corn produced 3-methyl-6-methoxy-8-hydroxy-3,4-dihydroisocoumarin which was extracted and then purified by silica gel columns. The physical and spectral properties of the colorless crystals from methylene chloride:hexane were consistent with those published for 3-methyl-6-methoxy-8-hydroxy-3,4-dihydroisocoumarin. Yield of high purity 3-methyl-6-methoxy-8-hydroxy-3,4-dihydroisocoumarin was about 140 mg of corn per kg.Keywords
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