Mechanism of Antiviral Activity of 5-Ethyl-2′-Deoxyuridine
- 1 January 1987
- journal article
- abstracts
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 6 (1-2) , 421-422
- https://doi.org/10.1080/07328318708056244
Abstract
5-Ethyl-2′-deoxyurldine (EDU) is phosphorylated to a much greater extent by herpes simplex virus (HSV)-infected Vero cells than by mock-infected cells. Within the infected cells, EDU is preferentially incorporated into viral DNA and more inhibitory to viral than cellular DNA synthesisKeywords
This publication has 2 references indexed in Scilit:
- Antiviral activity of 5-ethyl-2'-deoxyuridine against herpes simplex viruses in cell culture, mice, and guinea pigsAntimicrobial Agents and Chemotherapy, 1985
- Comparison of topically applied 5-ethyl-2'-deoxyuridine and acyclovir in the treatment of cutaneous herpes simplex virus infection in guinea pigsAntimicrobial Agents and Chemotherapy, 1985