Suzuki cross-coupling mediated by tetradentate N-heterocyclic carbene (NHC)–palladium complexes in an environmentally benign solvent
- 1 January 2003
- journal article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 1 (10) , 1643-1646
- https://doi.org/10.1039/b302646a
Abstract
A highly effective, easy to handle and environmentally benign process for palladium mediated Suzuki cross-coupling was developed. By utilizing a solid support based NHC–palladium catalyst, cross couplings of aryl bromides with phenylboronic acid were achieved in neat water under air. A high ratio of substrate to catalyst was also realized.Keywords
This publication has 25 references indexed in Scilit:
- Palladium-bisimidazol-2-ylidene complexes as catalysts for general and efficient Suzuki cross-coupling reactions of aryl chlorides with arylboronic acidsTetrahedron Letters, 2000
- Highly Active Palladium Catalysts for Suzuki Coupling ReactionsJournal of the American Chemical Society, 1999
- Palladium/P,O-Ligand-Catalyzed Suzuki Cross-Coupling Reactions of Arylboronic Acids and Aryl Chlorides. Isolation and Structural Characterization of (P,O)-Pd(dba) ComplexThe Journal of Organic Chemistry, 1999
- Palladium−Imidazol-2-ylidene Complexes as Catalysts for Facile and Efficient Suzuki Cross-Coupling Reactions of Aryl Chlorides with Arylboronic AcidsThe Journal of Organic Chemistry, 1999
- Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995–1998Journal of Organometallic Chemistry, 1999
- A Convenient and General Method for Pd-Catalyzed Suzuki Cross-Couplings of Aryl Chlorides and Arylboronic AcidsAngewandte Chemie International Edition in English, 1998
- Chelating N-heterocyclic carbene ligands in palladium-catalyzed heck-type reactionsJournal of Organometallic Chemistry, 1998
- Catalytic cross-coupling reactions in biaryl synthesisTetrahedron, 1998
- Palladium-Catalyzed Cross-Coupling Reactions of Organoboron CompoundsChemical Reviews, 1995
- The Palladium-Catalyzed Cross-Coupling Reaction of Phenylboronic Acid with Haloarenes in the Presence of BasesSynthetic Communications, 1981