Faculty Opinions recommendation of The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance.

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Abstract
This important study shows that bisphenol A (BPA), a compound that leaches from many types of commonly used plastics, leads to a rapid increase in plasma insulin and a drop in blood glucose, followed by chronic hyperinsulinemia and peripheral insulin resistance. BPA was first developed as a synthetic estrogen and is here shown to mimic several of the effects of estrogen on glucose homeostasis. The major significance of this...

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