Ent-kaurane Diterpenoids from Isodon rubescens var. lushanensis
- 1 January 2003
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 51 (7) , 790-793
- https://doi.org/10.1248/cpb.51.790
Abstract
Four new ent-kaurane diterpenoids lushanrubescensins F—I (1—4), together with 11 known ones, lasiodonin (5), oridonin (6), ponicidin (7), isodonoiol (8), isodonal (9), rabdosin B (10), rabdoternins A and B (11 and 12), enmenol (13), epinodosin (14), and inflexusin (15), were isolated from Isodon rubescens var. lushanensis, and the structures were elucidated by spectroscopic analysis. The inhibitory effect against the K562, Bcap37, BGC823, BIU87, CA, CNE, and Hela cell lines of compounds 3 and 5—10 were evaluated.Keywords
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