Acute Renal Failure Following Hypokalemic Rhabdomyolysis due to Chronic Glycyrrhizic Acid Administration.
- 1 January 1992
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 31 (5) , 708-711
- https://doi.org/10.2169/internalmedicine.31.708
Abstract
A 72-year-old man developed acute renal failure (ARF) following severe hypokalemic rhabdomyolysis. The hypokalemia was due to chronic glycyrrhizin (glycyrrhizic acid) administration. Although glycyrrhizin-induced hypokalemic rhabdomyolysis has been occasionally reported, the association of this type of rhabdomyolysis with ARF has not been described. In the present case, there was a sensitivity to glycyrrhizin the preceding renal insufficiency, and dehydration which was thought to have contributed to ARF. It should be recognized that elderly patients with such predisposing factors may be susceptible to a rapid deterioration of renal function after glycyrrhizin-induced hypokalemic rhabdomyolysis.Keywords
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