CIRCULATORY EFFECTS OF PERITONEAL INSUFFLATION WITH NITROUS OXIDE

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Abstract
The haemodynamic response to peritoneal insufflation with nitrous oxide was examined. Measurements were made during a control period, following peritoneal insufflation, and after release of the gas from the peritoneal cavity. A consistent fall in cardiac output and a rise in mean arterial pressure, central venous pressure and heart rate were observed following peritoneal insufflation with nitrous oxide. The fall in cardiac output differs from previous findings, when carbon dioxide was used as the gas for insufflation. Reasons for this difference are suggested and the implications of the observations are discussed.

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