Cerebral Atrophy Following ACTH Therapy
- 1 February 1980
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Computer Assisted Tomography
- Vol. 4 (1) , 20-23
- https://doi.org/10.1097/00004728-198002000-00004
Abstract
In a study of 15 patients with infantile spasms and Lennox syndrome, 4 (26.7%) showed no cerebral atrophy and 11 (73.3%) showed mild ventricular and sulcal enlargement before ACTH therapy. Ventricular and sulcal enlargement increased soon after ACTH therapy in most patients. Cerebral atrophy was reversible at over 1 mo. after ACTH therapy. In 3 instances, cerebral atrophy was not reversible as observed with computed tomography; 1 patient with infantile spasms had chronic subdural effusion, which appeared to be a complication of treatment with ACTH. Patients on ACTH therapy should be carefully monitored.This publication has 1 reference indexed in Scilit:
- Steroids and Apparent Cerebral Atrophy on Computed Tomography ScansJournal of Computer Assisted Tomography, 1978