Cerebral Ischemic Infarction in Paroxysmal Nocturnal Hemoglobinuria
- 18 July 2005
- journal article
- case report
- Published by Springer Nature in Zeitschrift für Neurologie
- Vol. 252 (11) , 1379-1386
- https://doi.org/10.1007/s00415-005-0871-3
Abstract
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder, leading to a deficient biosynthesis of surface proteins in hematopoetic cells. Clinical symptoms consist of various combinations of intravascular hemolysis, bone marrow failure and mainly venous thrombotic events. Arterial thrombosis has been described only in a few cases.Keywords
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