Lymphomas in the Wistar Rat After Intrapleural Inoculation of Silica
- 1 July 1972
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 49 (1) , 81-92
- https://doi.org/10.1093/jnci/49.1.81
Abstract
Crystalline silica was injected into the pleural cavity of standard and specific pathogen-free (SPF) Wistar rats; 39 of 95 SPF rats and 31 of 94 standard rats developed reticuloendothelial tumors, while another third had a “hvperplestic reaction.” The distribution of the silica and of the tumor masses is described together with the histology. Results from an inhalation experiment are briefly compared.Keywords
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