Differential Regulation of Enteric and Systemic Salmonellosis by slyA
- 1 September 1999
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 67 (9) , 4950-4954
- https://doi.org/10.1128/iai.67.9.4950-4954.1999
Abstract
Mutation of slyA , which reduces Salmonella typhimurium virulence in mice, caused only minor attenuation of S. typhimurium virulence in orally inoculated calves. This correlated with modest reductions in intestinal invasion and enteropathogenic responses in bovine ligated ileal loops. slyA appears to regulate virulence genes involved in systemic, but not enteric, salmonellosis.Keywords
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